The Haemophilus influenzae vaccine protects against which serotype?

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Multiple Choice

The Haemophilus influenzae vaccine protects against which serotype?

Explanation:
This vaccine is targeted to the capsule of a single serotype. Haemophilus influenzae has several serotypes distinguished by their capsule polysaccharides, and the Hib vaccine is a conjugate vaccine using the type b capsule (polyribosylribitol phosphate, PRP) attached to a protein carrier to boost immunity in young children. Antibodies against the type b capsule prevent invasive disease caused by Haemophilus influenzae type b, such as meningitis. Other serotypes (a, c, d) have different capsules, or non-typable strains lack a capsule altogether, so they aren’t covered by the Hib vaccine. Thus, protection is specifically against Haemophilus influenzae type b.

This vaccine is targeted to the capsule of a single serotype. Haemophilus influenzae has several serotypes distinguished by their capsule polysaccharides, and the Hib vaccine is a conjugate vaccine using the type b capsule (polyribosylribitol phosphate, PRP) attached to a protein carrier to boost immunity in young children. Antibodies against the type b capsule prevent invasive disease caused by Haemophilus influenzae type b, such as meningitis. Other serotypes (a, c, d) have different capsules, or non-typable strains lack a capsule altogether, so they aren’t covered by the Hib vaccine. Thus, protection is specifically against Haemophilus influenzae type b.

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