The extended-spectrum beta-lactamases confer resistance to which antibiotic?

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Multiple Choice

The extended-spectrum beta-lactamases confer resistance to which antibiotic?

Explanation:
Extended-spectrum beta-lactamases inactivate beta-lactam antibiotics by breaking the beta-lactam ring. Ceftriaxone is a third-generation cephalosporin, a type of beta-lactam, so bacteria producing ESBLs are typically resistant to ceftriaxone. The other drugs listed are not beta-lactams (am I kin to amikacin is an aminoglycoside; erythromycin a macrolide; rifampin a rifamycin), so they are not inherently affected by ESBLs through this mechanism. In infections with ESBL producers, ceftriaxone would be ineffective, guiding clinicians toward alternative treatments such as carbapenems.

Extended-spectrum beta-lactamases inactivate beta-lactam antibiotics by breaking the beta-lactam ring. Ceftriaxone is a third-generation cephalosporin, a type of beta-lactam, so bacteria producing ESBLs are typically resistant to ceftriaxone. The other drugs listed are not beta-lactams (am I kin to amikacin is an aminoglycoside; erythromycin a macrolide; rifampin a rifamycin), so they are not inherently affected by ESBLs through this mechanism. In infections with ESBL producers, ceftriaxone would be ineffective, guiding clinicians toward alternative treatments such as carbapenems.

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