The classic toxigenic strains of which serogroup are implicated in epidemic infections of Vibrio cholerae?

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Multiple Choice

The classic toxigenic strains of which serogroup are implicated in epidemic infections of Vibrio cholerae?

Explanation:
Epidemic cholera is driven by toxigenic strains of Vibrio cholerae that belong to serogroup O1. These strains carry the cholera toxin gene (CTX) and have caused the major outbreaks in history, with two biotypes within this serogroup—the classical and El Tor—both capable of producing the toxin and driving epidemics. Other serogroups such as O2, O3, and O4 are not the classic sources of epidemic cholera, though they can cause sporadic or milder disease. A separate serogroup, O139, has also caused outbreaks in some regions, but the classic epidemic strains are linked to O1.

Epidemic cholera is driven by toxigenic strains of Vibrio cholerae that belong to serogroup O1. These strains carry the cholera toxin gene (CTX) and have caused the major outbreaks in history, with two biotypes within this serogroup—the classical and El Tor—both capable of producing the toxin and driving epidemics. Other serogroups such as O2, O3, and O4 are not the classic sources of epidemic cholera, though they can cause sporadic or milder disease. A separate serogroup, O139, has also caused outbreaks in some regions, but the classic epidemic strains are linked to O1.

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